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Animal studies used doses up to 1.1 mg per kilogram of body weight with no adverse effects observed

Lidocaine hydrochloride blocks sodium ions from entering nerve membranes, which prevents nerve signal transmission and provides rapid local anesthesia

In this current trial with four participants enrolled, intracranial electroencephalography (iEEG) electrodes are implanted in the brain of a person with obesity suffering from loss of control eating, similar to the devices used to study and treat drug-resistant epilepsy and Parkinsons disease

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She has a background as a nurse and I have no concerns going into procedures with her - I know her procedure room is clean and safe and I will be well-cared for

However, the adverse events were described as mainly transient and mild-to-moderate in severity